Caenorhabditis Elegans Homologues
|
Vertebrate
Protein
with PubMed search by days old |
C.
Elegans Protein
|
Function
|
Sequence
Identity |
Reference
|
|
ß-Catenin
|
WRM-1
BAR-1 HMP-2 |
WRM-1:
Opposes Wnt signalling
BAR-1: Patterning events during larval development HMP-2: Cellular adhesion |
WRM-1:
15% HMP-2: 26% |
|
|
Tcf
|
POP-1
|
Repressor
in Wnt pathway
|
54%
(within HMG Box) |
|
|
Alpha-Catenin
|
HMP-1
|
Binds
and bundles actin filaments
|
35-38%
|
|
|
ß-Catenin / ARM
|
HMP-2 |
Cellular
adhesion
|
26%
|
|
|
Classical Cadherins
|
HMR-1
|
Interacts
with HMP-2
|
20-25%
|
